Fasting for a week:

  • Causes significant changes in protein levels across various organs.
  • May have health benefits beyond weight loss, but only after 3 days.
  • Switches energy source from glucose to fat after 2-3 days.
  • Average weight loss of 5.7 kg (fat and muscle), with most fat loss sustained after 3 days of eating.

Implications:

  • Provides insights into the molecular basis of fasting’s health effects.
  • Paves the way for developing alternative treatments based on fasting benefits.
  • Confirms historical use of fasting for specific health conditions.
  • PrincessLeiasCat@sh.itjust.works
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    7 months ago

    Causes your metabolism to lower while you’re restricting calories, or potentially for good?

    I ask because I ended up doing this pretty drastically for a time (long story, not proud of it) but once I started eating “normally” again, could my metabolism speed up again?

    • Fedizen@lemmy.world
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      7 months ago

      My understanding is that severe shifts in calorie intake vs output can lead to lasting metabolic changes. I think the main example people point to is that all “biggest loser” contestants failed to keep their weight down even when they maintained their diets and exercise for a long period.

      • Socsa@sh.itjust.works
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        7 months ago

        It’s not really metabolic per se, but hormonal. Hunger is hormone driven. If you restrict calories, you recalibrate your hormonal response to fullness and hunger.